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Quantification of Hsp90 availability reveals differential coupling to the heat shock response
The heat shock response (HSR) is a protective gene expression program that is activated by conditions that cause proteotoxic stress. While it has been suggested that the availability of free chaperones regulates the HSR, chaperone availability and the HSR have never been precisely quantified in tand...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219726/ https://www.ncbi.nlm.nih.gov/pubmed/30131327 http://dx.doi.org/10.1083/jcb.201803127 |