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Intronless mRNAs transit through nuclear speckles to gain export competence

Nuclear speckles (NSs) serve as splicing factor storage sites. In this study, we unexpectedly found that many endogenous intronless mRNAs, which do not undergo splicing, associate with NSs. These associations do not require transcription, polyadenylation, or the polyA tail. Rather, exonic splicing e...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Wang, Lantian, Wang, Jianshu, Chen, Suli, Shi, Min, Cheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219727/
https://www.ncbi.nlm.nih.gov/pubmed/30194269
http://dx.doi.org/10.1083/jcb.201801184