A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation

TPL-2 MAP 3-kinase promotes inflammation in numerous mouse disease models and is an attractive anti-inflammatory drug target. However, TPL-2–deficient (Map3k8(−/−)) mice develop exacerbated allergic airway inflammation to house dust mite (HDM) compared with wild type controls. Here, we show that Map...

Descripción completa

Detalles Bibliográficos
Autores principales: Ventura, Sonia, Cano, Florencia, Kannan, Yashaswini, Breyer, Felix, Pattison, Michael J., Wilson, Mark S., Ley, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219730/
https://www.ncbi.nlm.nih.gov/pubmed/30337469
http://dx.doi.org/10.1084/jem.20170852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219730/
https://www.ncbi.nlm.nih.gov/pubmed/30337469
http://dx.doi.org/10.1084/jem.20170852

Ejemplares similares