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SOX4 controls invariant NKT cell differentiation by tuning TCR signaling

Natural killer T (NKT) cells expressing the invariant T cell receptor (iTCR) serve an essential function in clearance of certain pathogens and have been implicated in autoimmune and allergic diseases. Complex effector programs of these iNKT cells are wired in the thymus, and upon thymic egress, they...

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Detalles Bibliográficos
Autores principales: Malhotra, Nidhi, Qi, Yilin, Spidale, Nicholas A., Frascoli, Michela, Miu, Bing, Cho, Okhyun, Sylvia, Katelyn, Kang, Joonsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219734/
https://www.ncbi.nlm.nih.gov/pubmed/30287480
http://dx.doi.org/10.1084/jem.20172021