Human monocytes and macrophages regulate immune tolerance via integrin αvβ8–mediated TGFβ activation

Monocytes are crucial immune cells involved in regulation of inflammation either directly or via differentiation into macrophages in tissues. However, many aspects of how their function is controlled in health and disease are not understood. Here we show that human blood monocytes activate high leve...

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Detalles Bibliográficos
Autores principales: Kelly, Aoife, Gunaltay, Sezin, McEntee, Craig P., Shuttleworth, Elinor E., Smedley, Catherine, Houston, Stephanie A., Fenton, Thomas M., Levison, Scott, Mann, Elizabeth R., Travis, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219736/
https://www.ncbi.nlm.nih.gov/pubmed/30355614
http://dx.doi.org/10.1084/jem.20171491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219736/
https://www.ncbi.nlm.nih.gov/pubmed/30355614
http://dx.doi.org/10.1084/jem.20171491

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