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Transient T-bet expression functionally specifies a distinct T follicular helper subset

T follicular helper (Tfh) cells express transcription factor BCL-6 and cytokine IL-21. Mature Tfh cells are also capable of producing IFN-γ without expressing the Th1 transcription factor T-bet. Whether this IFN-γ–producing Tfh population represents a unique Tfh subset with a distinct differentiatio...

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Detalles Bibliográficos
Autores principales: Fang, Difeng, Cui, Kairong, Mao, Kairui, Hu, Gangqing, Li, Rao, Zheng, Mingzhu, Riteau, Nicolas, Reiner, Steven L., Sher, Alan, Zhao, Keji, Zhu, Jinfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219743/
https://www.ncbi.nlm.nih.gov/pubmed/30232200
http://dx.doi.org/10.1084/jem.20180927