Cargando…

Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells

Immunotherapy approaches stand out as innovative strategies to eradicate tumor cells. Among them, PD-1/PD-L1 immunotherapy is considered one of the most successful advances in the history of cancer immunotherapy. We used our technology of Polypurine reverse Hoogsteen hairpins (PPRHs) for silencing b...

Descripción completa

Detalles Bibliográficos
Autores principales: Medina Enríquez, Miriam Marlene, Félix, Alex J., Ciudad, Carlos J., Noé, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219785/
https://www.ncbi.nlm.nih.gov/pubmed/30399174
http://dx.doi.org/10.1371/journal.pone.0206818