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Clustering-local-unique-enriched-signals (CLUES) promotes identification of novel regulators of ES cell self-renewal and pluripotency

BACKGROUND: Key regulators of developmental processes can be prioritized through integrated analysis of ChIP-Seq data of master transcriptional factors (TFs) such as Nanog and Oct4, active histone modifications (HMs) such as H3K4me3 and H3K27ac, and repressive HMs such as H3K27me3. Recent studies sh...

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Detalles Bibliográficos
Autores principales: Wu, Chao, Jiao, Yang, Shen, Manli, Pan, Chen, Cheng, Guo, Jia, Danmei, Zhu, Jing, Zhang, Long, Zheng, Min, Jia, Junling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219791/
https://www.ncbi.nlm.nih.gov/pubmed/30399165
http://dx.doi.org/10.1371/journal.pone.0206844