Miransertib (ARQ 092), an orally-available, selective Akt inhibitor is effective against Leishmania

Leishmaniasis is amongst the most important neglected diseases, afflicting more than 12 million people in 88 countries. There is an urgent need for safe orally bioavailable and cost-effective drugs for the treatment of leishmaniasis. It has recently been shown that Leishmania activates host macropha...

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Detalles Bibliográficos
Autores principales: Nandan, Devki, Zhang, Naixin, Yu, Yi, Schwartz, Brian, Chen, Stella, Kima, Peter E., Reiner, Neil E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219794/
https://www.ncbi.nlm.nih.gov/pubmed/30399177
http://dx.doi.org/10.1371/journal.pone.0206920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219794/
https://www.ncbi.nlm.nih.gov/pubmed/30399177
http://dx.doi.org/10.1371/journal.pone.0206920

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