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Miransertib (ARQ 092), an orally-available, selective Akt inhibitor is effective against Leishmania
Leishmaniasis is amongst the most important neglected diseases, afflicting more than 12 million people in 88 countries. There is an urgent need for safe orally bioavailable and cost-effective drugs for the treatment of leishmaniasis. It has recently been shown that Leishmania activates host macropha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219794/ https://www.ncbi.nlm.nih.gov/pubmed/30399177 http://dx.doi.org/10.1371/journal.pone.0206920 |