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Proteome-scale understanding of relationship between homo-repeat enrichments and protein aggregation properties
Expansion of homo-repeats is a molecular basis for human neurological diseases. We are the first who studied the influence of homo-repeats with lengths larger than four amino acid residues on the aggregation properties of 1449683 proteins across 122 eukaryotic and bacterial proteomes. Only 15% of pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219797/ https://www.ncbi.nlm.nih.gov/pubmed/30399196 http://dx.doi.org/10.1371/journal.pone.0206941 |