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Mito-mice∆ and mitochondrial DNA mutator mice as models of human osteoporosis caused not by aging but by hyperparathyroidism

Mitochondrial DNA (mtDNA) mutator mice showing accelerated accumulation of mtDNA with somatic mutations are potentially useful models of human aging, whereas mito-miceΔ showing accelerated accumulation of mtDNA with a deletion mutation (ΔmtDNA) are potentially useful models of mitochondrial diseases...

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Detalles Bibliográficos
Autores principales: Mito, Takayuki, Tani, Haruna, Suzuki, Michiko, Ishikawa, Kaori, Nakada, Kazuto, Hayashi, Jun-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219885/
https://www.ncbi.nlm.nih.gov/pubmed/29973435
http://dx.doi.org/10.1538/expanim.18-0060