Development and clinical assessment of new objective adherence markers for four microbicide delivery systems used in HIV prevention studies

BACKGROUND: Adherence is critical for successful topical, vaginally delivered anti-retroviral (ARV)-based HIV pre-exposure prophylaxis (PrEP). Quantitating systemic or tissue ARV levels through LC–MS/MS is currently viewed as the most reliable measure of adherence. However, for placebo-controlled tr...

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Detalles Bibliográficos
Autores principales: Jacot, Terry A., Clark, Meredith R., Adedipe, Oluwatosin E., Godbout, Susan, Peele, Abby G., Ju, Susan, Schwartz, Jill L., Thurman, Andrea R., Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219998/
https://www.ncbi.nlm.nih.gov/pubmed/30402770
http://dx.doi.org/10.1186/s40169-018-0213-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219998/
https://www.ncbi.nlm.nih.gov/pubmed/30402770
http://dx.doi.org/10.1186/s40169-018-0213-6

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