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Determining the Balance Between Drug Efficacy and Safety by the Network and Biological System Profile of Its Therapeutic Target
One of the most challenging puzzles in drug discovery is the identification and characterization of candidate drug of well-balanced profile between efficacy and safety. So far, extensive efforts have been made to evaluate this balance by estimating the quantitative structure–therapeutic relationship...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220079/ https://www.ncbi.nlm.nih.gov/pubmed/30429792 http://dx.doi.org/10.3389/fphar.2018.01245 |