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Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer

Oncological use of anti-angiogenic VEGF inhibitors has been limited by the lack of informative biomarkers. Previously we reported circulating Tie2 as a vascular response biomarker for bevacizumab-treated ovarian cancer patients. Using advanced MRI and circulating biomarkers we have extended these fi...

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Detalles Bibliográficos
Autores principales: Jayson, Gordon C., Zhou, Cong, Backen, Alison, Horsley, Laura, Marti-Marti, Kalena, Shaw, Danielle, Mescallado, Nerissa, Clamp, Andrew, Saunders, Mark P., Valle, Juan W., Mullamitha, Saifee, Braun, Mike, Hasan, Jurjees, McEntee, Delyth, Simpson, Kathryn, Little, Ross A., Watson, Yvonne, Cheung, Susan, Roberts, Caleb, Ashcroft, Linda, Manoharan, Prakash, Scherer, Stefan J., del Puerto, Olivia, Jackson, Alan, O’Connor, James P. B., Parker, Geoff J. M., Dive, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220185/
https://www.ncbi.nlm.nih.gov/pubmed/30405103
http://dx.doi.org/10.1038/s41467-018-07174-1