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Gene inversion potentiates bacterial evolvability and virulence
Most bacterial genes are encoded on the leading strand, co-orienting the movement of the replication machinery with RNA polymerases. This bias reduces the frequency of detrimental head-on collisions between the two machineries. The negative outcomes of these collisions should lead to selection again...
Autores principales: | Merrikh, Christopher N., Merrikh, Houra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220195/ https://www.ncbi.nlm.nih.gov/pubmed/30405125 http://dx.doi.org/10.1038/s41467-018-07110-3 |
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