Structural effects and lymphocyte activation properties of self-assembled polysaccharide nanogels for effective antigen delivery

The success of immunotherapeutic vaccines is often limited by their inability to activate the cytotoxic T lymphocyte (CTL)-inducing Th1 pathway. We investigated the ability of self-assembled nanogels (CHP or CH-CDex) to activate this pathway, and characterised them chemically and biologically. Once...

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Detalles Bibliográficos
Autores principales: Miura, Risako, Tahara, Yoshiro, Sawada, Shin-ichi, Sasaki, Yoshihiro, Akiyoshi, Kazunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220277/
https://www.ncbi.nlm.nih.gov/pubmed/30405172
http://dx.doi.org/10.1038/s41598-018-34885-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220277/
https://www.ncbi.nlm.nih.gov/pubmed/30405172
http://dx.doi.org/10.1038/s41598-018-34885-8

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