Epithelial cells release adenosine to promote local TNF production in response to polarity disruption

Disruption of epithelial integrity contributes to chronic inflammatory disorders through persistent activation of stress signalling. Here we uncover a mechanism whereby disruption of apico-basal polarity promotes stress signalling. We show that depletion of Scribbled (Scrib), a baso-lateral determin...

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Detalles Bibliográficos
Autores principales: Poernbacher, Ingrid, Vincent, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220285/
https://www.ncbi.nlm.nih.gov/pubmed/30405122
http://dx.doi.org/10.1038/s41467-018-07114-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220285/
https://www.ncbi.nlm.nih.gov/pubmed/30405122
http://dx.doi.org/10.1038/s41467-018-07114-z

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