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USP14 inhibition corrects an in vivo model of impaired mitophagy

Mitochondrial autophagy or mitophagy is a key process that allows selective sequestration and degradation of dysfunctional mitochondria to prevent excessive reactive oxygen species, and activation of cell death. Recent studies revealed that ubiquitin–proteasome complex activity and mitochondrial mem...

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Detalles Bibliográficos
Autores principales: Chakraborty, Joy, von Stockum, Sophia, Marchesan, Elena, Caicci, Federico, Ferrari, Vanni, Rakovic, Aleksandar, Klein, Christine, Antonini, Angelo, Bubacco, Luigi, Ziviani, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220287/
https://www.ncbi.nlm.nih.gov/pubmed/30249595
http://dx.doi.org/10.15252/emmm.201809014