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Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum

Epigenetic mechanisms, such as CpG DNA methylation enable phenotypic plasticity and rapid adaptation to changing environments. CpG DNA methylation is established by DNA methyltransferases (DNMTs), which are well conserved across vertebrates and invertebrates. There are insects with functional DNA me...

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Detalles Bibliográficos
Autores principales: Schulz, Nora K. E., Wagner, C. Isabel, Ebeling, Julia, Raddatz, Günter, Diddens-de Buhr, Maike F., Lyko, Frank, Kurtz, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220294/
https://www.ncbi.nlm.nih.gov/pubmed/30405203
http://dx.doi.org/10.1038/s41598-018-34701-3