Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion

The epithelial-to-mesenchymal transition (EMT) is an important mechanism for cancer progression and metastasis. Numerous in vitro and tumor-profiling studies point to the miR-200–Zeb1 axis as crucial in regulating this process, yet in vivo studies involving its regulation within a physiological cont...

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Detalles Bibliográficos
Autores principales: Title, Alexandra C., Hong, Sue-Jean, Pires, Nuno D., Hasenöhrl, Lynn, Godbersen, Svenja, Stokar-Regenscheit, Nadine, Bartel, David P., Stoffel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220299/
https://www.ncbi.nlm.nih.gov/pubmed/30405106
http://dx.doi.org/10.1038/s41467-018-07130-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220299/
https://www.ncbi.nlm.nih.gov/pubmed/30405106
http://dx.doi.org/10.1038/s41467-018-07130-z

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