Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator

Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored in a mouse model of tauopathy following t...

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Detalles Bibliográficos
Autores principales: Chatterjee, Snehajyoti, Cassel, Raphaelle, Schneider‐Anthony, Anne, Merienne, Karine, Cosquer, Brigitte, Tzeplaeff, Laura, Halder Sinha, Sarmistha, Kumar, Manoj, Chaturbedy, Piyush, Eswaramoorthy, Muthusamy, Le Gras, Stéphanie, Keime, Céline, Bousiges, Olivier, Dutar, Patrick, Petsophonsakul, Petnoi, Rampon, Claire, Cassel, Jean‐Christophe, Buée, Luc, Blum, David, Kundu, Tapas K, Boutillier, Anne‐Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220301/
https://www.ncbi.nlm.nih.gov/pubmed/30275019
http://dx.doi.org/10.15252/emmm.201708587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220301/
https://www.ncbi.nlm.nih.gov/pubmed/30275019
http://dx.doi.org/10.15252/emmm.201708587

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