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High Expression of Glycolytic Genes in Cirrhosis Correlates With the Risk of Developing Liver Cancer

A marked increase in the rate of glycolysis is a key event in the pathogenesis of hepatocellular carcinoma (HCC), the main type of primary liver cancer. Liver cirrhosis is considered to be a key player in HCC pathogenesis as it precedes HCC in up to 90% of patients. Intriguingly, the biochemical eve...

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Detalles Bibliográficos
Autores principales: Lee, Nathan C. W., Carella, Maria Annunziata, Papa, Salvatore, Bubici, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220322/
https://www.ncbi.nlm.nih.gov/pubmed/30430110
http://dx.doi.org/10.3389/fcell.2018.00138