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Polymer–Temozolomide Conjugates as Therapeutics for Treating Glioblastoma
[Image: see text] A series of polymer–drug conjugates based on 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared with the glioblastoma drug temozolomide (TMZ) as pendent groups. Random and block copolymers were synthesized by reversible addition–fragmentation chain-transfer (RAFT) polymeri...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220362/ https://www.ncbi.nlm.nih.gov/pubmed/30354145 http://dx.doi.org/10.1021/acs.molpharmaceut.8b00766 |