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Polymer–Temozolomide Conjugates as Therapeutics for Treating Glioblastoma

[Image: see text] A series of polymer–drug conjugates based on 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared with the glioblastoma drug temozolomide (TMZ) as pendent groups. Random and block copolymers were synthesized by reversible addition–fragmentation chain-transfer (RAFT) polymeri...

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Detalles Bibliográficos
Autores principales: Ward, Sarah M., Skinner, Matthew, Saha, Banishree, Emrick, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220362/
https://www.ncbi.nlm.nih.gov/pubmed/30354145
http://dx.doi.org/10.1021/acs.molpharmaceut.8b00766