Relevance of Trypanothione Reductase Inhibitors on Trypanosoma cruzi Infection: A Systematic Review, Meta-Analysis, and In Silico Integrated Approach

Due to the rudimentary antioxidant defenses in Trypanosoma cruzi, disruptors of redox balance are promising candidates for new antitrypanosomal drugs. We developed an integrated model based on systematic review, meta-analyses, and molecular modeling to evaluate the effect of trypanothione reductase...

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Detalles Bibliográficos
Autores principales: Mendonça, Andréa Aparecida Santos, Coelho, Camila Morais, Veloso, Marcia Paranho, Caldas, Ivo Santana, Gonçalves, Reggiani Vilela, Teixeira, Antônio Lucio, de Miranda, Aline Silva, Novaes, Rômulo Dias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220389/
https://www.ncbi.nlm.nih.gov/pubmed/30473742
http://dx.doi.org/10.1155/2018/8676578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220389/
https://www.ncbi.nlm.nih.gov/pubmed/30473742
http://dx.doi.org/10.1155/2018/8676578

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