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Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study
BACKGROUND: Causal associations between microglia activation and β-amyloid (Aβ) accumulation during the progression of Alzheimer’s disease (AD) remain a matter of controversy. Therefore, we used longitudinal dual tracer in vivo small animal positron emission tomography (μPET) imaging to resolve the...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220478/ https://www.ncbi.nlm.nih.gov/pubmed/30400912 http://dx.doi.org/10.1186/s12974-018-1347-6 |