Metformin Improves Neurologic Outcome Via AMP‐Activated Protein Kinase–Mediated Autophagy Activation in a Rat Model of Cardiac Arrest and Resuscitation

BACKGROUND: Sudden cardiac arrest (CA) often results in severe injury to the brain, and neuroprotection after CA has proved to be difficult to achieve. Herein, we sought to investigate the effects of metformin pretreatment on brain injury secondary to CA and cardiopulmonary resuscitation. METHODS AN...

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Detalles Bibliográficos
Autores principales: Zhu, Juan, Liu, Kewei, Huang, Kaibin, Gu, Yong, Hu, Yafang, Pan, Suyue, Ji, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220525/
https://www.ncbi.nlm.nih.gov/pubmed/29895585
http://dx.doi.org/10.1161/JAHA.117.008389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220525/
https://www.ncbi.nlm.nih.gov/pubmed/29895585
http://dx.doi.org/10.1161/JAHA.117.008389

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