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Relaxin Family Member Insulin‐Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models

BACKGROUND: The insulin/insulin‐like growth factor/relaxin family represents a group of structurally related but functionally diverse proteins. The family member relaxin‐2 has been evaluated in clinical trials for its efficacy in the treatment of acute heart failure. In this study, we assessed the r...

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Detalles Bibliográficos
Autores principales: Maruyama, Sonomi, Wu, Chia‐Ling, Yoshida, Sumiko, Zhang, Dongying, Li, Pei‐Hsuan, Wu, Fangzhou, Parker Duffen, Jennifer, Yao, Rouan, Jardin, Blake, Adham, Ibrahim M., Law, Ronald, Berger, Joel, Di Marchi, Richard, Walsh, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220528/
https://www.ncbi.nlm.nih.gov/pubmed/29887522
http://dx.doi.org/10.1161/JAHA.117.008441