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NADPH Oxidase 5 Is a Pro‐Contractile Nox Isoform and a Point of Cross‐Talk for Calcium and Redox Signaling‐Implications in Vascular Function

BACKGROUND: NADPH Oxidase 5 (Nox5) is a calcium‐sensitive superoxide‐generating Nox. It is present in lower forms and higher mammals, but not in rodents. Nox5 is expressed in vascular cells, but the functional significance remains elusive. Given that contraction is controlled by calcium and reactive...

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Detalles Bibliográficos
Autores principales: Montezano, Augusto C., De Lucca Camargo, Livia, Persson, Patrik, Rios, Francisco J., Harvey, Adam P., Anagnostopoulou, Aikaterini, Palacios, Roberto, Gandara, Ana Caroline P., Alves‐Lopes, Rheure, Neves, Karla B., Dulak‐Lis, Maria, Holterman, Chet E., de Oliveira, Pedro Lagerblad, Graham, Delyth, Kennedy, Christopher, Touyz, Rhian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220544/
https://www.ncbi.nlm.nih.gov/pubmed/29907654
http://dx.doi.org/10.1161/JAHA.118.009388