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NADPH Oxidase 5 Is a Pro‐Contractile Nox Isoform and a Point of Cross‐Talk for Calcium and Redox Signaling‐Implications in Vascular Function
BACKGROUND: NADPH Oxidase 5 (Nox5) is a calcium‐sensitive superoxide‐generating Nox. It is present in lower forms and higher mammals, but not in rodents. Nox5 is expressed in vascular cells, but the functional significance remains elusive. Given that contraction is controlled by calcium and reactive...
Autores principales: | Montezano, Augusto C., De Lucca Camargo, Livia, Persson, Patrik, Rios, Francisco J., Harvey, Adam P., Anagnostopoulou, Aikaterini, Palacios, Roberto, Gandara, Ana Caroline P., Alves‐Lopes, Rheure, Neves, Karla B., Dulak‐Lis, Maria, Holterman, Chet E., de Oliveira, Pedro Lagerblad, Graham, Delyth, Kennedy, Christopher, Touyz, Rhian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220544/ https://www.ncbi.nlm.nih.gov/pubmed/29907654 http://dx.doi.org/10.1161/JAHA.118.009388 |
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