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Extracellular Vesicle Injection Improves Myocardial Function and Increases Angiogenesis in a Swine Model of Chronic Ischemia

BACKGROUND: Mesenchymal stem cell–derived extracellular vesicles (EVs) are believed to be cardioprotective in myocardial infarct. The objective of this study was to examine the effects of human mesenchymal cell–derived EV injection on cardiac function, myocardial blood flow, and vessel density in th...

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Detalles Bibliográficos
Autores principales: Potz, Brittany A., Scrimgeour, Laura A., Pavlov, Vasile I., Sodha, Neel R., Abid, M. Ruhul, Sellke, Frank W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220556/
https://www.ncbi.nlm.nih.gov/pubmed/29895586
http://dx.doi.org/10.1161/JAHA.117.008344