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Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin

HCN1 compartmentalization in CA1 pyramidal cells, essential for hippocampal information processing, is believed to be controlled by the extracellular matrix protein Reelin. Expression of Reelin, in turn, is stimulated by 17β-estradiol (E2). In this study, we therefore tested whether E2 regulates the...

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Detalles Bibliográficos
Autores principales: Meseke, Maurice, Neumüller, Florian, Brunne, Bianka, Li, Xiaoyu, Anstötz, Max, Pohlkamp, Theresa, Rogalla, Meike M., Herz, Joachim, Rune, Gabriele M., Bender, Roland A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220572/
https://www.ncbi.nlm.nih.gov/pubmed/30406178
http://dx.doi.org/10.1523/ENEURO.0258-18.2018