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Enlarged Optic Nerve Axons and Reduced Visual Function in Mice with Defective Microfibrils

Glaucoma is a leading cause of irreversible vision loss due to retinal ganglion cell (RGC) degeneration that develops slowly with age. Elevated intraocular pressure (IOP) is a significant risk factor, although many patients develop glaucoma with IOP in the normal range. Mutations in microfibril-asso...

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Detalles Bibliográficos
Autores principales: Wu, Hang-Jing, Hazlewood, Ralph J., Kuchtey, John, Kuchtey, Rachel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220594/
https://www.ncbi.nlm.nih.gov/pubmed/30406200
http://dx.doi.org/10.1523/ENEURO.0260-18.2018