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Interfilament interaction between IMPDH and CTPS cytoophidia

Inosine monophosphate dehydrogenase (IMPDH) and cytidine triphosphate synthase (CTPS) are two metabolic enzymes that perform rate‐limiting steps in the de novo synthesis of purine and pyrimidine nucleotides, respectively. It has been shown that IMPDH and CTPS can comprise a filamentous macrostructur...

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Detalles Bibliográficos
Autores principales: Chang, Chia‐Chun, Keppeke, Gerson D., Sung, Li‐Ying, Liu, Ji‐Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220823/
https://www.ncbi.nlm.nih.gov/pubmed/30085408
http://dx.doi.org/10.1111/febs.14624