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Modified Peptide Inhibitors of the Keap1–Nrf2 Protein–Protein Interaction Incorporating Unnatural Amino Acids
Noncovalent inhibitors of the Keap1–Nrf2 protein–protein interaction (PPI) have therapeutic potential in a range of disease states including neurodegenerative diseases (Parkinson's and Alzheimer's diseases), chronic obstructive pulmonary disease and various inflammatory conditions. By stal...
Autores principales: | Georgakopoulos, Nikolaos D., Talapatra, Sandeep K., Gatliff, Jemma, Kozielski, Frank, Wells, Geoff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220877/ https://www.ncbi.nlm.nih.gov/pubmed/29927029 http://dx.doi.org/10.1002/cbic.201800170 |
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