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Generation of the UFM1 Toolkit for Profiling UFM1‐Specific Proteases and Ligases

Ubiquitin‐fold modifier 1 (UFM1) is a reversible post‐translational modifier that is covalently attached to target proteins through an enzymatic cascade and removed by designated proteases. Abnormalities in this process, referred to as Ufmylation, have been associated with a variety of human disease...

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Detalles Bibliográficos
Autores principales: Witting, Katharina F., van der Heden van Noort, Gerbrand J., Kofoed, Christian, Talavera Ormeño, Cami, el Atmioui, Dris, Mulder, Monique P. C., Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220884/
https://www.ncbi.nlm.nih.gov/pubmed/30188611
http://dx.doi.org/10.1002/anie.201809232