Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice

Mucosa‐associated lymphoid tissue 1 (Malt1) regulates immune cell function by mediating the activation of nuclear factor κB (NF‐κB) signaling through both its adaptor and proteolytic function. Malt1 is also a target of its own protease activity and this self‐cleavage further contributes to NF‐κB act...

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Detalles Bibliográficos
Autores principales: Baens, Mathijs, Stirparo, Rocco, Lampi, Youlia, Verbeke, Delphine, Vandepoel, Roel, Cools, Jan, Marynen, Peter, de Bock, Charles E., Bornschein, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Tumor immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220888/
https://www.ncbi.nlm.nih.gov/pubmed/30025160
http://dx.doi.org/10.1002/eji.201847597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220888/
https://www.ncbi.nlm.nih.gov/pubmed/30025160
http://dx.doi.org/10.1002/eji.201847597

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