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Modeling how reversal of immune exhaustion elicits cure of chronic hepatitis C after the end of treatment with direct‐acting antiviral agents

A fraction of chronic hepatitis C patients treated with direct‐acting antivirals (DAAs) achieved sustained virological responses (SVR), or cure, despite having detectable viremia at the end of treatment (EOT). This observation, termed EOT (+)/SVR, remains puzzling and precludes rational optimization...

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Detalles Bibliográficos
Autores principales: Baral, Subhasish, Roy, Rahul, Dixit, Narendra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220890/
https://www.ncbi.nlm.nih.gov/pubmed/29744934
http://dx.doi.org/10.1111/imcb.12161