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Phase I trial of active specific immunotherapy with autologous dendritic cells pulsed with autologous irradiated tumor stem cells in hepatitis B‐positive patients with hepatocellular carcinoma

BACKGROUND AND OBJECTIVES: Hepatocellular carcinoma (HCC) is often associated with chronic hepatitis due to hepatitis‐B or ‐C viruses. Active specific immunotherapy (ASI) with autologous dendritic cells (DC) presenting antigens from autologous tumor stem cell (TC) lines is associated with promising...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojin, Bayer, Michael E., Chen, Xiaosong, Fredrickson, Craig, Cornforth, Andrew N., Liang, Greg, Cannon, Jessica, He, Jia, Fu, Qingchun, Liu, Jia, Nistor, Gabriel I., Cao, Wei, Chen, Chengwei, Dillman, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220948/
https://www.ncbi.nlm.nih.gov/pubmed/25873455
http://dx.doi.org/10.1002/jso.23897