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Syndecan‐4 influences mammalian myoblast proliferation by modulating myostatin signalling and G1/S transition
Myostatin, a TGF‐β superfamily member, is a negative regulator of muscle growth. Here we describe how myostatin activity is regulated by syndecan‐4, a ubiquitous transmembrane heparan sulfate proteoglycan. During muscle regeneration the levels of both syndecan‐4 and promyostatin decline gradually af...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221024/ https://www.ncbi.nlm.nih.gov/pubmed/30129974 http://dx.doi.org/10.1002/1873-3468.13227 |