CRISPR/Cas9‐mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV‐positive hepatocellular carcinoma cells

Chronic hepatitis B virus (HBV) infection remains the most common risk factor for hepatocellular carcinoma (HCC). High HBV surface antigen (HBsAg) levels are highly correlated with hepatocarcinogenesis and HBV‐associated HCC development. However, the role and detailed mechanisms associated with HBsA...

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Detalles Bibliográficos
Autores principales: Song, Jia, Zhang, Xiaochao, Ge, Qianyun, Yuan, Chaoyi, Chu, Liang, Liang, Hui‐fang, Liao, Zhibin, Liu, Qiumeng, Zhang, Zhanguo, Zhang, Bixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221038/
https://www.ncbi.nlm.nih.gov/pubmed/29904948
http://dx.doi.org/10.1002/jcb.27050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221038/
https://www.ncbi.nlm.nih.gov/pubmed/29904948
http://dx.doi.org/10.1002/jcb.27050

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