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Bayesian selective response‐adaptive design using the historical control

High quality historical control data, if incorporated, may reduce sample size, trial cost, and duration. A too optimistic use of the data, however, may result in bias under prior‐data conflict. Motivated by well‐publicized two‐arm comparative trials in stroke, we propose a Bayesian design that both...

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Detalles Bibliográficos
Autores principales: Kim, Mi‐Ok, Harun, Nusrat, Liu, Chunyan, Khoury, Jane C., Broderick, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221103/
https://www.ncbi.nlm.nih.gov/pubmed/29900577
http://dx.doi.org/10.1002/sim.7836