Hepatocyte‐like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers

Direct reprogramming represents an easy technique to generate induced hepatocytes (iHeps) from somatic cells. However, current protocols are accompanied by several drawbacks as iHeps are heterogenous and lack fully mature phenotypes of primary hepatocytes. Here, we established a polycistronic expres...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Pla‐Palacín, Iris, Baptista, Pedro M., Shang, Peng, Oosterhoff, Loes A., van Wolferen, Monique E., Penning, Louis C., Geijsen, Niels, Spee, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221165/
https://www.ncbi.nlm.nih.gov/pubmed/29959867
http://dx.doi.org/10.1002/bit.26784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221165/
https://www.ncbi.nlm.nih.gov/pubmed/29959867
http://dx.doi.org/10.1002/bit.26784

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