Sialic acid facilitates binding and cytotoxic activity of the pore-forming Clostridium perfringens NetF toxin to host cells

NetF-producing type A Clostridium perfringens is an important cause of canine and foal necrotizing enteritis. NetF, related to the β-sheet pore-forming Leukocidin/Hemolysin superfamily, is considered a major virulence factor for this disease. The main purpose of this work is to demonstrate the pore-...

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Detalles Bibliográficos
Autores principales: Mehdizadeh Gohari, Iman, Brefo-Mensah, Eric K., Palmer, Michael, Boerlin, Patrick, Prescott, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221314/
https://www.ncbi.nlm.nih.gov/pubmed/30403719
http://dx.doi.org/10.1371/journal.pone.0206815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221314/
https://www.ncbi.nlm.nih.gov/pubmed/30403719
http://dx.doi.org/10.1371/journal.pone.0206815

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