Endothelial Cell–Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature

OBJECTIVE—: Blood-CNS (central nervous system) barrier defects are implicated in retinopathies, neurodegenerative diseases, stroke, and epilepsy, yet, the pathological mechanisms downstream of barrier defects remain incompletely understood. Blood-retina barrier (BRB) formation and retinal angiogenes...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Lai, Maria B., Pedler, Michelle G., Johnson, Verity, Adams, Ralf H., Petrash, J. Mark, Chen, Zhe, Junge, Harald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221394/
https://www.ncbi.nlm.nih.gov/pubmed/30354230
http://dx.doi.org/10.1161/ATVBAHA.118.311689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221394/
https://www.ncbi.nlm.nih.gov/pubmed/30354230
http://dx.doi.org/10.1161/ATVBAHA.118.311689

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