The Novel Neuroprotective Compound KMS99220 Has an Early Anti-neuroinflammatory Effect via AMPK and HO-1, Independent of Nrf2

We have previously reported a novel synthetic compound KMS99220 that prevented degeneration of the nigral dopaminergic neurons and the associated motor deficits, suggesting a neuroprotective therapeutic utility for Parkinson's disease. Microglia are closely associated with neuroinflammation, wh...

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Detalles Bibliográficos
Autores principales: Lee, Ji Ae, Kim, Hye Ri, Kim, Jiyoung, Park, Ki Duk, Kim, Dong Jin, Hwang, Onyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221835/
https://www.ncbi.nlm.nih.gov/pubmed/30429650
http://dx.doi.org/10.5607/en.2018.27.5.408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221835/
https://www.ncbi.nlm.nih.gov/pubmed/30429650
http://dx.doi.org/10.5607/en.2018.27.5.408

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