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The Novel Neuroprotective Compound KMS99220 Has an Early Anti-neuroinflammatory Effect via AMPK and HO-1, Independent of Nrf2
We have previously reported a novel synthetic compound KMS99220 that prevented degeneration of the nigral dopaminergic neurons and the associated motor deficits, suggesting a neuroprotective therapeutic utility for Parkinson's disease. Microglia are closely associated with neuroinflammation, wh...
Autores principales: | Lee, Ji Ae, Kim, Hye Ri, Kim, Jiyoung, Park, Ki Duk, Kim, Dong Jin, Hwang, Onyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Brain and Neural Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221835/ https://www.ncbi.nlm.nih.gov/pubmed/30429650 http://dx.doi.org/10.5607/en.2018.27.5.408 |
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