iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia

Disease modeling of Alzheimer's disease (AD) has been hampered by the lack of suitable cellular models while animal models are mainly based on the overexpression of AD-related genes which often results in an overemphasis of certain pathways and is also confounded by aging. In this study, we the...

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Detalles Bibliográficos
Autores principales: Li, Ling, Roh, Jee Hoon, Chang, Eun Hyuk, Lee, Yoonkyung, Lee, Suji, Kim, Minchul, Koh, Wonyoung, Chang, Jong Wook, Kim, Hee Jin, Nakanishi, Mahito, Barker, Roger A., Na, Duk L., Song, Jihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221836/
https://www.ncbi.nlm.nih.gov/pubmed/30429645
http://dx.doi.org/10.5607/en.2018.27.5.350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221836/
https://www.ncbi.nlm.nih.gov/pubmed/30429645
http://dx.doi.org/10.5607/en.2018.27.5.350

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