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Decreased Protein Quality Control Promotes the Cognitive Dysfunction Associated With Aging and Environmental Insults
Background: Most neurodegenerative diseases are sporadic and develop with age. Degenerative neural tissues often contain intra- and extracellular protein aggregates, suggesting that the proteostasis network that combats protein misfolding could be dysfunctional in the setting of neurodegenerative di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221900/ https://www.ncbi.nlm.nih.gov/pubmed/30443201 http://dx.doi.org/10.3389/fnins.2018.00753 |