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Decreased Protein Quality Control Promotes the Cognitive Dysfunction Associated With Aging and Environmental Insults

Background: Most neurodegenerative diseases are sporadic and develop with age. Degenerative neural tissues often contain intra- and extracellular protein aggregates, suggesting that the proteostasis network that combats protein misfolding could be dysfunctional in the setting of neurodegenerative di...

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Detalles Bibliográficos
Autores principales: Jin, Hisayo, Komita, Mari, Aoe, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221900/
https://www.ncbi.nlm.nih.gov/pubmed/30443201
http://dx.doi.org/10.3389/fnins.2018.00753