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Early Growth Response Gene-2 Is Essential for M1 and M2 Macrophage Activation and Plasticity by Modulation of the Transcription Factor CEBPβ

The process of macrophage polarization is involved in many pathologies such as anti-cancer immunity and autoimmune diseases. Polarized macrophages exhibit various levels of plasticity when M2/M(IL-4) macrophages are reprogrammed into an M1-like phenotype following treatment with IFNγ and/or LPS. At...

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Detalles Bibliográficos
Autores principales: Veremeyko, Tatyana, Yung, Amanda W. Y., Anthony, Daniel C., Strekalova, Tatyana, Ponomarev, Eugene D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221966/
https://www.ncbi.nlm.nih.gov/pubmed/30443252
http://dx.doi.org/10.3389/fimmu.2018.02515